glomerular thrombosis 20xWEB

Glomerular thrombosis (H&E 20X)

“As is our pathology—so is our practice.” (Sir William Osler)

In its best form, the practice of pathology is grounded solidly in the practice of clinical medicine, and benefits from a functional union of clinicians and pathologists. The surgical pathologist depends on the clinician to provide adequate clinical information accompanying the specimen, good biopsy procedure and submission of case materials, clear communication, and follow-up clinical information when appropriate. The clinician depends on the pathologist to provide a report that is accurate and clinically relevant, to be available for consultation, and also to provide feedback and education regarding the quality and diagnostic value of the submitted samples submitted. Ultimately, it is not the clinician’s nor the pathologist’s interest that is served in this relationship, but rather that of the patient.  This is always our goal at SpecialtyVETPATH.  

We offer expertise in Oncopathology, Gastroenteropathology, Neuropathology, and Hepatobiliary, Ophthalmic, and Musculoskeletal Pathology.  Please see below for more information about these specific services.  

plasma cell tumor 40XWEB

Plasma cell tumor (H&E 40X)

Surgical margins of excisional biopsies (suspected or confirmed neoplasms) are inked during gross evaluation and prior to sectioning.  Ancillary diagnostics such as immunochemistry may be recommended in some cases.

We will assign numerical grades to tumors where there is an established and clinically relevant grading system. In other instances, malignancies will be evaluated as low or high grade on the basis of more general features such as mitotic index, degree of anaplasia, and evidence of invasiveness.  

Some of the most common tumor grading systems are listed below:



Centrilobular necrosis: acute Sago palm toxicosis (H&E 10X)

Centrilobular necrosis: acute Sago palm toxicosis (H&E 10X)

Diseases of the liver and biliary system play an important role in both general and specialty veterinary practice. When performed, processed, and interpreted with care and expertise, liver biopsy can be a powerful tool in the workup of a patient with liver or/and biliary disease. Both the pathologist and the clinician have specific responsibilities in this regard, and will ideally work together in order to maximize the diagnostic value of biopsies submitted for evaluation.  Special stains may be beneficial to better evaluate certain hepatic lesions and will be pursued as deemed necessary by the pathologist.  

Small intestinal lymphoma, feline (H&E 20X)

Small intestinal lymphoma, feline (H&E 20X)

Endoscopic and surgical biopsies can provide important information in the diagnostic workup of gastrointestinal disease in small animals, provided careful attention is taken to avoid errors in acquisition, processing, and interpretation. Both the pathologist and the clinician have specific responsibilities and will ideally work together in order to maximize the diagnostic value of biopsies submitted for evaluation.  

Please see our Biopsy and Submission Guidelines prior to submission.

Panophthalmitis (H&E 2X)

Panophthalmitis (H&E 2X)

For submission of enucleation specimens: include history, ophthalmic exam findings, results of other laboratory testing if pertinent, and clinical differential diagnosis. This is particularly important as it may influence how the globe is sectioned and what sections are examined.  Unless the lesion submitted for evaluation includes or is limited to the eyelids or other periocular tissues, these should be removed prior to placing the globe in formalin in order to allow optimal fixation.  If eyelids and periocular tissue are not removed, eyelid sutures should be removed to allow formalin to more readily perfuse the globe.

Protozoal encephalitis: Toxoplasma gondii (H&E 40X)

Protozoal encephalitis: Toxoplasma gondii (H&E 40X)

All submissions should be accompanied by a thorough clinical history, results of clinical testing, and clinical differential diagnosis. When submitting whole brains, please include clinical neuroanatomic lesion localization and results of imaging studies (when available). Electronic images and copies of other laboratory tests can be sent to Please include patient name in the subject line when submitting electronic files.

Fibrous Osteodystropy Renal Failure

Fibrous Osteodystropy: Renal Failure

For many disease processes affecting skeletal muscle in small animals, routine H&E and histochemical staining of formalin-fixed tissue is sufficient for diagnosis. However, sometimes it is desirable to examine frozen sections for diagnosis of muscle diseases. Please contact us if you are uncertain what tissue to submit or for specific instructions on submission of fresh tissue when indicated.

Please provide a thorough clinical history as well as digital radiographs and/or radiology reports when submitting bone biopsies, digits, or limb amputations. Electronic files can be sent to (include patient name in subject line).